Learn about test-tube baby in Thailand, good single embryo transfer or multiple embryo transfer
Release time：2018-06-13Source：XYCC Click on：
In Thailand, test-tube babies were made up with seven or eight embryos. Why did they only transplant one embryo? Perhaps many people have such questions. Leilei International stated that transplanting multiple embryos will increase the chance of conception, but multiple pregnancy will affect the mother's body. And the harm of the fetus, but few people care. Those mothers and fetuses who are pregnant with multiple births will face various health problems such as pregnancy-induced hypertension, hyperemesis gravidarum, placenta previa, intrauterine growth retardation, premature rupture of membranes, gestational diabetes, postpartum hemorrhage In addition to fetal transfusion syndrome, there are often preterm births that require hospitalization, and even individual preterm infants may leave some unhealthy diseases.
For good single embryo transfer or multi-embryo transplantation, we can first look at the risk of multiple embryo transfer.
First, the mother side
1, hypertensive disorders during pregnancy
It is a disease that is unique during pregnancy. It used to be a pregnancy-induced hypertension syndrome. Pregnant women with multiple pregnancies (especially those in the first trimester) will over-inflate, cause intrauterine pressure to rise, decrease or slow down blood flow to the uterus and placenta, cause ischemia and hypoxia, blood pressure may increase due to vasospasm, and pregnancy may occur. Hypertensive disease.
The disease occurred after 20 weeks of pregnancy. Pregnant women showed high blood pressure, edema, proteinuria, severe convulsions, coma, organ failure, and even maternal death.
PIH can cause complications such as heart disease with pregnancy-induced hypertension, placental abruption, coagulation dysfunction, cerebral hemorrhage, renal failure, and postpartum blood circulation failure, which seriously endangers the safety of the mother and fetus and is one of the major causes of preterm birth. .
2, pregnancy vomiting
Pregnancy vomiting refers to the recurrent nausea, vomiting, anorexia, or vomiting as the main symptoms of early pregnancy reactions between 2 and 3 months of pregnancy. It is currently recognized that vomiting in pregnancy is associated with elevated levels of chorionic gonadotropin (HCG) in pregnant women's blood, which is a normal phenomenon.
Severe early pregnancy reaction, frequent vomiting, can not eat, so that the occurrence of body fluid imbalance and metabolic disorders, severe pregnancy will endanger the life, known as hyperemesis gravidarum. In pregnant women with multiple pregnancies, the rate of hyperemesis due to hyperglycemia is higher as the HCG value increases significantly.
3, placenta previa
Placenta is normally attached to the posterior, anterior or lateral wall of the uterus. If the placenta is attached to the lower part of the uterus or is covered at the inner os of the cervix, it is located below the exposed part of the fetus and is referred to as the placenta previa. Placenta previa is one of the major causes of late pregnancy bleeding and is a serious complication during pregnancy.
Due to multiple placentas in multiple pregnancies, the volume of the placenta increases and the risk of placenta previa increases. Scientists have found that the incidence of placenta previa in twins is twice that of singletons. Placenta previa is prone to bleeding before production, and it is not possible to maintain pregnancy to full term. Premature birth and high perinatal mortality rate occur.
4, premature rupture of membranes
Before the childbirth, the rupture of the fetal membranes was called premature rupture of the membranes.
As the uterus grows during pregnancy, the membranes are stretched and the intrauterine pressure increases. The multiple pregnancy leads to excessive pressure in the uterine cavity, too much amniotic fluid, and the cervix cannot withstand the gradual increase of normal pressure and expansion. The fetal membranes also follow. The extension of the ectocervix to the cervix or even the vagina leads to the formation of the anterior amniotic sac, the diameter of the anterior amniotic sac gradually increases, the tensile force of the fetal membrane increases, the membrane stretches, and eventually ruptures beyond the elastic strength of the membrane. Eventually lead to miscarriage.
5, gestational diabetes
Women who do not have diabetes, when they have glucose tolerance during pregnancy, are called "gestational diabetes." There are many factors associated with gestational diabetes, and multiple pregnancy is also one of the main factors. If a pregnant woman is over 30 years old and is also a multiple pregnancy, her chances of having gestational diabetes are much higher than average. The main risk of gestational diabetes is that it may cause fetal congenital malformations, neonatal hypoglycemia and respiratory distress syndrome, stillbirth, polyhydramnios, premature birth, pregnant women urinary tract infections, headaches, etc., not only affect the development of the fetus, but also harm the health of the mother.
6, postpartum hemorrhage
In the case of multiple pregnancy, due to over-expansion of the uterus, the uterine fibers are overstretched, degenerative lesions occur, the number of peduncles increases, muscle fibers decrease and contraction is weak, and postpartum hemorrhage is caused, which seriously jeopardizes the life safety of pregnant women and is a maternal death. The first reason.
Second, the fetus, newborn
Intrauterine growth retardation
Intrauterine growth retardation (IUGR) refers to the birth weight of the fetus less than the tenth percentile or two standard deviations of the average weight of the same gestational age. If the gestational age has reached 37 weeks and the newborn's weight is less than 2.5 kg, it is also called intrauterine growth retardation.
Through the previous introduction, we can see that the risk of multiple pregnancies is not only related to the number of embryos, but also has a close relationship with age. Therefore, Leilei International's proposal is: For patients under the age of 35, normal ovarian reserve function can be achieved by selecting high-quality single embryo transfer to obtain a higher embryo implantation rate and clinical pregnancy rate, while reducing the multiple pregnancy rate.
However, it is still meaningful to transplant 2 to 3 embryos at the age of 37 or older women who have failed IVF. Because with the increase of age, the clinical pregnancy rate showed a downward trend, and the spontaneous abortion rate showed an upward trend. To ensure the success rate, only a few embryos could be transplanted.
For prospective parents in the IVF cycle, do not blindly pursue multiple births, or give birth to babies with health and safety, measure their own physical condition comprehensively, and listen to doctors to determine the number of embryos to be transplanted.
The success rate of test-tube baby in Thailand is not 100%, and the success rate of test-tube baby in Thailand is relatively high. The surgeon should be prepared for the failure of transplantation and maintain an optimistic attitude. It will help to increase the success rate.